Postdoctoral Associate

Summary

We employ untargeted and targeted metabolomic analysis and isotope tracing studies using newlyvested in-house Thermo Exploris 480 LC/MS instrument. Along with this powerful analytical tool, weuse various in vivo mouse models and in vitro models to define the role of nutritional input and theunderlying mechanisms in disease development and control. For instance, we have recently (Nature,2019) employed metabolomics approaches to show that dietary methionine restriction is an effectiveand feasible dietary intervention in healthy humans and mice to alter circulating metabolism withoutovert side effect. Dietary methionine restriction has shown promising in various mouse cancer modelsalone or in combination with chemotherapy or radiotherapy.

Job Duties

• Performs research under the general direction of the Principal Investigator.
• Plans, directs, and conducts metabolomics and metabolic flux studies, and others as they emerge.
• Collects and analyzes data, and prepare slides, figures and manuscripts for publications.
• Develops new research directions.
• Trains new lab members, junior lab members, and students.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Three years of relevant experience typically as a Research Assistant, Research Technician or PhD.
• PhDs interested in our research and with prior experience or expertise in analytical chemistry and metabolism are encouraged to apply.
• Metabolomics and Mass Spectrometry.
• At least three years of experience.